منابع مشابه
MicroRNA-221-222 regulate the cell cycle in mast cells.
MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that have emerged as key posttranscriptional regulators in a wide variety of organisms. Because any one miRNA can potentially regulate expression of a distinct set of genes, differential miRNA expression can shape the repertoire of proteins that are actually expressed during development and differentiation or disease. Here, we...
متن کاملMicrorna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells
BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression. They negatively regulate gene expression post-transcriptionally by translational repression and target mRNA degradation. miRNAs have been shown to play crucial roles in muscle development and in regulation of muscle cell proliferation and differentiation. M...
متن کاملThe role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines.
Androgen-dependent prostate cancer typically progresses to castration-resistant prostate cancer (CRPC) after the androgen deprivation therapy. MicroRNAs (miR) are noncoding small RNAs (19-25nt) that play an important role in the regulation of gene expression. Recent studies have shown that miR expression patterns are significantly different in normal and neoplastic prostate epithelial cells. Ho...
متن کاملMicroRNA-222 Expression and Its Prognostic Potential in Non-Small Cell Lung Cancer
Overexpression of miR-222 has been found in several types of cancers; however, the expression of miR-222 in non-small cell lung cancer (NSCLC) and its prognostic values are unclear. This study aimed to investigate whether the miR-222 expression level is related to clinicopathological factors and prognosis of NSCLC. Through a prospective study, 100 pairs of NSCLC tissues and adjacent normal tiss...
متن کاملSerum level of microRNA-222 acts as a diagnostic and prognostic biomarker for osteosarcoma patients
Dysregulated expression profiles of microRNAs (miRNAs) and their roles in diagnosis and prognosis of osteosarcoma patients have attracted much attention. Although miR-222 has been shown to be important in several cancers, its roles in osteosarcoma remain unknown. Hence, in this study, we focused on the expression and further to evaluate the clinicopathological, diagnostic and prognostic value o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44535